Aurobindo Pharma USA is continuously striving to achieve product differentiation, specifically through formulation development and novel delivery methods of complex products.
Research & Development
Numerous delivery methods are being developed in drug product including:
Oral
- Work on complex oral dosage forms including Osmotically Controlled Release Systems (OROS) based dosage, solutions and suspension and Hot Melt Extrusion (HME)
- High potency compounds including potent compound suites (RD & Commercial) that control the rate at which an active ingredient is released
- Develop and manufacture complex dosage forms using controlled drug substances (DEA schedule 1-4) to enable Abuse Deterrent Formulations (ADF) and REMS program drugs
Injectables
- Working on complex injectable products in the field of sustained drug delivery including depot formulation, suspensions and polymer based products
- For more information please visit, AuroMedics
Specialty Products
Aurobindo has a 40,000 sq. ft. state-of-the-art R&D and pilot plant facility in Durham, North Carolina. Further, build-out of a cGMP manufacturing facility for commercialization of specialty products on the same site has commenced. The R&D labs site houses over 50 scientists, including highly experienced pMDI aerosol, topical and transdermal R&D teams, with associated analytical and testing labs.
Inhalation
- Products under development include pMDIs, which comprise a drug formulation in an HFA (Hydro Fluoro Alkanes) propellant system, filled under pressure in metal canisters with crimped metered dosing valves and actuators to guide the aerosol spray
Topical
- Developments underway on a large portfolio of topical solutions, ointments, creams, gels and topical OTC products that act locally
- For more information on OTC products, please visit Aurohealth
Transdermal
- Development is underway for a matrix adhesive transdermal patch that acts systemically
- Technology of the matrix adhesive patch enables the active ingredients to be formulated within the adhesive matrix, coated onto a backing liner and protected with a release liner that is removed prior to application
Other Research & Development Capabilities
- A portfolio of products under development for nasal and ophthalmic delivery